MOTS-c and the Retinal Microenvironment: Metabolic Coordination of Cellular Response under HEV Stress
Abstract
A systematic literature review exploring the mitochondrial-derived peptide MOTS-c, its cellular uptake, and reported pathways modulating metabolic homeostasis, AMPK activation, and cell survival under high-energy visible (HEV) photo-oxidative stress. Surveyed purely as reference literature; no clinical outcomes are claimed.
Methods
- 01Scope : MOTS-c mitochondrial bioenergetics
- 02Sources : primary published cellular and animal research (2015-2026)
- 03Mechanisms : AMPK phosphorylation, GLUT4 activation, ROS suppression
- 04Framing : neutral literature synthesis without meta-analysis
DISCLOSURE : This report presents anonymized in-silico and/or observational reference data. It does not establish a causal relationship between any catalogued material and any physiological outcome, and it is not a claim of safety, efficacy, or benefit.
Compounds referenced
This note surveys published work on the following compound. They are research materials, not treatments, and nothing here indicates they are suitable for any use in humans.