RESEARCH LABORATORY USE ONLY · NOT FOR HUMAN OR ANIMAL CONSUMPTION

fovea.bio
Eye & Vision Research · Independent Laboratory

The science of
human vision,
cell by cell.

An independent laboratory dedicated to the eye. Vision begins at the fovea, the pinpoint of sharpest sight, travels through the retinal ganglion cells (RGCs), and is powered every step by mitochondria. Reference-grade compounds, characterized to ≥99% purity and modeled in-house against their molecular targets.

Materials are supplied strictly for in-vitro laboratory research. Not for human or veterinary use. No therapeutic claim is made.

Laboratory Diagnostics · Active
ANALYTICAL ARRAY
3/5
Active
99.6%
Sequence Match
0
Cycles
  • HPLC-01RP-HPLCSS-31 Purity Verification94%
  • MS-02ESI-TOF MSMOTS-c Sequence Identity88%
  • LAL-01Kinetic LALOcular Safety Endotoxin Check61%
  • NMR-03¹H-NMRPinealon Structural Analysis76%
  • LYO-04DesiccatorEpitalon Vacuum LyophilizationQUE

The Catalogue · At a Glance

Lyophilized reference vials, each characterized, sealed, and documented for retinal and cellular research.

All Materials
≥99%
HPLC purity

Reference spec for all peptide & cofactor standards in the catalogue.

LC-MS
Identity confirmed

Mass-spectrometric verification of molecular identity per lot.

3rd-party
Independent analytics

Certificates issued by external analytical laboratories.

Per-lot
Purity Assured

Each batch is analytically verified for high precision.

The Anatomy of Vision : Eye, Brain, Longevity

From the macula and fovea, through the retina's neurons, down the optic nerve to the visual cortex, and across the aging of the whole system. Every structure mapped, and linked to the materials studied against it.

Interactive Anatomy MappingClick structures to inspect
CORNEALENSVITREOUSIRISRETINAFOVEACONE/RODRGCNERVEV1 CORTEXMITOAGINGRetinal LayersCross-section detailNFLNerve Fiber LayerGCLGanglion Cell LayerIPL — Inner PlexiformINLInner Nuclear LayerOPL — Outer PlexiformONLOuter Nuclear LayerIS/OSPhotoreceptor SegmentsRPEPigment EpitheliumBruch's membraneLIGHTMitochondrionInner membrane & cristaemtDNAOuter membraneCristae (ETC complexes)MatrixATP →LIGHT
Central Visual HubActive Target

Macula & Fovea

The core visual center of the retina. Responsible for high-acuity daylight vision, the fovea is highly vulnerable to metabolic energy failure. Epitalon (AEDG) is studied here for protecting the supporting retinal pigment epithelium (RPE) cells to preserve central visual acuity.

Path Vulnerability
Critical Oxidative Load
ATP Reliance
Highest (98%)

Studied Target Reference Standards

SS-3110 mg

$75.00

Details
NAD⁺1000 mg

$90.00

Details
Epitalon10 mg

$70.00

Details
01

The Eye

Where light becomes signal, across the retina and the optic nerve head. This is where the research concentrates.

The Macula & Central Vision
Macula luteaSS-31NAD⁺EpitalonFovea centralisSS-31NAD⁺EpitalonFoveolaUmboFoveal avascular zoneNAD⁺MOTS-cSS-31
Photoreceptors & the Outer Retina
PhotoreceptorsSS-31NAD⁺EpitalonConesSS-31NAD⁺EpitalonRodsRetinal pigment epitheliumSS-31NAD⁺Epitalon
Inner Retinal Processing
Bipolar cellsHorizontal cellsAmacrine cellsInner plexiform layer
Retinal Ganglion Cells
Retinal Ganglion CellsNAD⁺SS-31PinealonMidget ganglion cellsParasol ganglion cellsBistratified ganglion cells
Nerve Fibre Layer & Optic Nerve
Retinal Nerve Fibre LayerNAD⁺SS-31PinealonAxonsOptic discLamina cribrosaNAD⁺PinealonOptic nerveNAD⁺SS-31PinealonMyelinOligodendrocytes
02

The Brain

Where signal becomes perception, from the chiasm to the visual cortex. Shown for completeness; not targeted by the materials.

The Central Visual Pathway
Optic chiasmDecussationOptic tractLateral Geniculate NucleusOptic radiationsPrimary Visual Cortex
03

Longevity

The systemic processes of aging that erode the whole pathway over decades.

Longevity & the Aging Visual System
NAD⁺ declineNAD⁺Telomere shorteningEpitalonCardiolipin oxidationSS-31Mitochondrial-derived peptidesMOTS-cCellular senescenceEpitalonNAD⁺Neuronal apoptosisPinealon

Why Vision Is an Energy Problem

Sharp central vision depends on the fovea and the retinal ganglion cells behind it: some of the most energy-hungry cells in the body. The research literature points to three stressors that drain that energy.

Screen Phototoxicity

Chronic high-energy visible (HEV) exposure is associated in the literature with cumulative photo-oxidative load on foveal photoreceptor and RGC mitochondria.

NAD⁺ Depletion

Tissue NAD⁺ pools decline with age and metabolic stress, constraining sirtuin/PARP-dependent maintenance pathways in high-demand neural tissue.

Cardiolipin Oxidation

Peroxidation of inner-membrane cardiolipin is described as an early event in mitochondrial dysfunction and intrinsic apoptotic signaling.

Neuronal Apoptosis

Age-related accumulation of neuronal cell death driven by oxidative damage and caspase activation, with retinal ganglion cells among the most vulnerable CNS neurons.

The reference materials catalogued here map to five nodes studied in this literature: a redox-cofactor substrate (NAD⁺), a chromatin-interacting tetrapeptide (Epitalon), a cardiolipin-associating tetrapeptide (SS-31), a neuroprotective tripeptide bioregulator (Pinealon), and a mitochondrial-derived peptide (MOTS-c). Their inclusion is descriptive of the published research; it is not a claim of efficacy, benefit, or fitness for any use in humans. All materials are currently available for pre-order.

The Reference Archive

The full set of characterized materials, at a glance.

Reference Process · Source to Release

A five-stage protocol from molecular identity to documented release.

STAGE 01

Sourcing & Identity

Reference materials are sourced and verified for molecular identity by LC-MS / MS prior to release.

STAGE 02

Purity Analytics

Independent HPLC quantifies purity against the published reference specification for each class.

STAGE 03

Lyophilization & Sealing

Materials are lyophilized and vacuum-sealed in amber vials to preserve integrity under cold storage.

STAGE 04

In-Silico Characterization

Selected materials enter the local compute array for flexible structural modeling and contact mapping.

STAGE 05

Documentation & Release

Materials are characterized and released strictly for laboratory research and reference use.

Computational Methodology

Beyond rigid virtual screening: toward flexible peptide–protein and peptide–DNA structural prediction.

Flexible Peptide–DNA Docking

All-atom prediction of peptide conformation within nucleic-acid grooves, scored by interface contact density and ΔG ensembles.

Membrane Association Modeling

Peptide–lipid association sampled in model bilayers, characterized by salt-bridge persistence and aromatic stacking occupancy.

Evolutionary-Scale Scoring

Protein language-model scoring (ESM-class) for sequence plausibility and zero-shot variant ranking ahead of physical simulation.

Peptide × DNA

AEDG in the hTERT promoter groove

Flexible all-atom docking of the Epitalon tetrapeptide against a model hTERT promoter duplex, scored by interface contact density and ΔG ensembles.

Read structural report
Peptide × Membrane

SS-31 × cardiolipin / PLSCR3

Membrane-embedded association modeling of SS-31 against cardiolipin and a PLSCR3 interface, characterized by salt-bridge persistence and stacking occupancy.

Read structural report
Peptide × DNA

EDR (Pinealon) × neuronal regulatory DNA

Flexible all-atom docking of the EDR tripeptide against neuronal gene regulatory domains, scored by minor-groove contact density and ΔG ensembles.

Read structural report

Verification & Trust

Every claim on this site is backed by analytics, not adjectives.

Third-Party Verified

Every lot is independently analyzed by external HPLC / LC-MS laboratories before release.

≥99% Purity

Peptide and cofactor standards are released only at ≥99% purity, across the full catalogue.

Independent Testing

Identity and purity are confirmed by independent HPLC/LC-MS testing before release.

Sealed & Lyophilized

Vacuum-sealed amber vials, lyophilized to preserve molecular integrity under cold storage.

In-House Validation

Each material is modeled against its molecular target on our secure cluster.

Transparent & RUO

A strict research-use-only mandate, documented references, and no marketing claims.

Purity guarantee: any lot that does not meet the ≥99% purity specification is replaced or refunded.

Frequently Asked

Common questions on scope, compliance, and analytics.

Full terms are documented in the Compliance repository.

Every material is supplied strictly for in-vitro laboratory research. Materials are not drugs, foods, cosmetics, or supplements, and are not for human or veterinary use, consumption, or administration by any route.

We do not require formal institutional credentials, but all orders require an explicit attestation at checkout that the materials are obtained solely for in-vitro laboratory research and reference use, and will not be administered to humans or animals.

Identity is confirmed by LC-MS / MS and purity by HPLC, with a reference spec of ≥99% for every peptide and cofactor standard in the catalogue.

Our secure cluster runs flexible peptide–protein and peptide–DNA structural prediction and all-atom dynamics. Outputs are anonymized structural reference data, not claims of physiological effect.

No. Nothing on this site has been evaluated by the FDA, and no statement is intended to diagnose, treat, cure, or prevent any disease. Research summaries describe published literature and in-house computation as reference material only.

Reference-grade materials. Documented analytics. Faceless rigor.

Access the catalogue of characterized research materials, each accompanied by lot-specific third-party analytics.